Mannitol is a six-carbon polyol extracted from brown algae cells and has two configurations, D and L. The L configuration is a synthetic product and does not exist in nature. The D configuration is widely distributed in the plant kingdom. Especially the marine brown algae in the kelp family is very high in content. Mannitol is a storage substance in brown algae cells. Large brown algae such as kelp are the main raw materials for the extraction of mannitol. The mannitol extracted from kelp and the mannitol nicotinate synthesized with niacin have a significant effect on angina pectoris and have a good effect on the Hyperlipidemia. It can treat high cholesterol, hypertension and arteriosclerosis. Mannitol is also a dehydrating agent and can be used medically. When injected into the vein with its 20% solution, it is rarely decomposed in the body, causing a temporary increase in blood osmotic pressure to allow water in the tissue to enter the blood, thereby reducing tissue edema. When mannitol is filtered from the glomeruli, it is not easily reabsorbed in the renal tubules, increasing the osmotic pressure of the original urine in the renal tubules, bringing out a large amount of water and playing a diuretic effect.
Mannitol is an isomer of sorbitol. Its molecular formula and molecular mass are the same as sorbitol. Sorbitol is very hygroscopic, but mannitol is not hygroscopic at all. The sweetness of mannitol is equivalent to 70% of the sugar in Sugarcane. The body can absorb, partially metabolize, and partially excrete from urine. Mannitol is mainly used in medicine and food, and can be used as food additives, sugar-free sweet food, feed additives.
Mannitol is a diuretic that is used to reduce swelling and pressure inside the eye or around the brain.
Mannitol is also used to help your body produce more urine. mannitol is used in people with kidney failure, to remove excess water and toxins from the body.
Mannitol is sometimes given so that your body will produce enough urine to be collected and tested. This helps your doctor determine if your kidneys are working properly.
Mannitol may also be used for purposes not listed in this medication guide.
Mannitol is one of the common sugar alcohol sugar substitutes, and is often used in sugar-free chewing gum ingredients. Mannitol is the least water-absorbing sugar alcohol and can be used as a food anti-sticking powder.
It is used as a large infusion for injection, used to reduce cerebral pressure, intraocular pressure, and eliminate cerebral edema; used as a diuretic; renal function and intestinal examination; oliguria and renal failure due to edema burns, mannitol infusion has a certain effect; System compound infusion. Because of its good compression properties, it has become an excellent excipient for the pharmaceutical industry. In addition, mannitol nitrogen mustard synthesized with mannitol as raw material and mannitol bismethanesulfonic acid as antitumor drugs are suitable for chronic leukemia.
Post time: May-28-2020