Rutin, also known as vitamin P, with molecular formula of C27H30O16, is a natural flavonoid glycoside, which belongs to flavonol glycosomes widely existing in plants. The two glycosomes are glucose and rhamnose. The appearance is light yellow or light green acicular crystal or crystalline powder. It can be dissolved in pyridine, formyl and alkaline solution, slightly soluble in ethanol, acetone and ethyl acetate, and almost insoluble in chloroform, ether, benzene, carbon disulfide and petroleum ether. It has anti-inflammatory, anti-oxidation, anti allergy, anti-virus and other effects.
Rutin has anti lipid peroxidation effect. Lipid peroxidation refers to a series of oxidation processes caused by reactive oxygen species attacking polyunsaturated fatty acids in biofilm. Zhu Jianlin et al. Found that rutin inhibited lipid peroxidation in ovariectomized rats and inhibited the decline of antioxidant capacity of antioxidant system after ovariectomy by measuring and analyzing SOD activity, MDA content of free radical lipid peroxidation product and lipofuscin content in rat liver. Rutin can resist the decline of antioxidant capacity caused by the decline of endogenous estrogen and has antioxidant effect.
Rutin can remove harmful free radicals in the body. Rutin is a flavonoid compound and a strong oxidant to remove free radicals. It can terminate the chain reaction of free radicals, inhibit the peroxidation of many unsaturated fatty acids on biofilm, remove lipid peroxidation products, protect the integrity of biofilm and subcellular structure, and plays an important role in the body.
Rutin can help the human body fight against pancreatitis. Rutin can effectively prevent hypocalcemia and reduce the concentration of Ca2 + in pancreatic tissue. Rutin can increase the content of phospholipase A2 (PLA2) in pancreatic tissue, suggesting that rutin may inhibit the release and activation of PLA2 in pancreatic tissue; Rutin can effectively prevent the occurrence of hypocalcemia in AP rats, which may reduce the pathophysiological damage to AP by preventing Ca2 + influx and reducing Ca2 + overload in pancreatic tissue cells.
Post time: Aug-02-2021