Rutin

Product Details

Name: Rutin

CAS: 153-18-4

Feature:

Rutin, also known as vitamin P, with molecular formula of c27h30o16, is a natural flavonoid glycoside, which belongs to flavonol glycosomes widely existing in plants. The two glycosomes are glucose and rhamnose. The appearance is light yellow or light green acicular crystal or crystalline powder. It can be dissolved in pyridine, formyl and alkaline solution, slightly soluble in ethanol, acetone and ethyl acetate, and almost insoluble in chloroform, ether, benzene, carbon disulfide and petroleum ether. It has anti-inflammatory, anti-oxidation, anti allergy, anti-virus and other effects.

Rutin has the following applications/functions:

Scavenging free radicals, Anti pancreatitis,Antagonism of platelet activating factor

1.Rutin can remove harmful free radicals in the body. Rutin is a flavonoid compound and a strong oxidant to remove free radicals. It can terminate the chain reaction of free radicals, inhibit the peroxidation of many unsaturated fatty acids on biofilm, remove lipid peroxidation products, protect the integrity of biofilm and subcellular structure, and plays an important role in the body.

2.Rutin can effectively prevent hypocalcemia and reduce the concentration of Ca²⁺ in pancreatic tissue. Rutin can increase the content of phospholipase A2 (PLA2) in pancreatic tissue, suggesting that rutin may inhibit the release and activation of PLA2 in pancreatic tissue; Rutin can effectively prevent the occurrence of hypocalcemia in AP rats, which may reduce the pathophysiological damage to AP by preventing Ca²⁺ influx and reducing Ca^{2 +} overload in pancreatic tissue cells.

3. Rutin can antagonize the effect of platelet activating factor. The pathogenesis of many cardiovascular and cerebrovascular diseases such as thrombosis, atherosclerosis, inflammatory reaction and ischemia-reperfusion free radical injury are closely related to the mediation of platelet activating factor. Therefore, antagonizing the effect of PAF is an important way to alleviate ischemic cardiovascular and cerebrovascular diseases. The results showed that rutin could antagonize the specific binding between PAF and rabbit platelet membrane receptor in a concentration dependent manner, and inhibit PAF mediated rabbit platelet adhesion and the increase of free Ca^{2 +} concentration in PMNs. It showed that the mechanism of rutin anti PAF was to inhibit the activation of PAF receptor and block the response induced by PAF, so as to protect cardiovascular system. The results showed that rutin was a PAF receptor antagonist.

Composition: 

Appearance: Light yellow powder

Assay: 98%

Packing: 25kg/drum or as discussed

Shelf Life: 2 years

Storage: Store in cool and dry area

Certification:ISO GMP KOSHER HALAL